Dr. Johnson was granted several US patents related to the biological function of protocatechuate; a.k.a protocatechuic acid (PCA). PCA is the primary metabolite from the dyes that make blueberries blue and cherries red. When one eats those fruits the dyes are rapidly and completely metabolized into PCA and absorbed into your blood steam. However, the amount possible by diet is far less than that which would have a significant biological effect. For instance, one would have to eat 18 pounds of blueberries, at once to have a therapeutic effect on the body.
However, when isolated in the pure concentrated form, protocatechuate has certain beneficial biological properties as established by the supporting evidence published in the following patents.
As a result of several years research in the laboratory and the clinic, the formulation of A-Cosmetic was discovered. This research included a two-year, four-phase study human study at Loma Linda Medical School looking for a pre-operative disinfectant. The effectiveness of the A-Cosmetic formulation was established with the potential to disinfect human skin of many potential pathogens, including Propionibacterium acnes. These discoveries have resulted in several United States patents (view specific patent claims below).